TY - JOUR
T1 - Effect of diethylstilbestrol on plasma testosterone levels during 24 hours
T2 - Study comparing doses of 1 and 5 mg daily, and 1 mg. 3 times daily
AU - Flores-Esteva, J.
AU - Medina-Santillan, R.
AU - Berea-Dominguez, H.
AU - Villalpando-Casas, J. J.
AU - Martínez-Romero, M. A.
AU - Navarrete, L. R.
AU - Martin-Lombard, M. E.
PY - 1980
Y1 - 1980
N2 - A study was done on 30 patients with advanced adenocarcinoma of the prostate treated with diethylstilbestrol. Three groups of patients were given daily doses of 1, 5 and 1 times 3 mg. diethylstilbestrol, respectively. The study was confined to the effects of treatment on the levels of plasma testosterone by taking hormonal specimens every 4 hours for 24 hours. The results showed little difference of plasma testosterone among the groups under study and a statistical analysis showed no significant differences. Therefore, our study showed no appreciable advantage in the dosage spread over the day, compared to commonly used doses of 1 or 5 mg. diethylstilbestrol given in a single dosage.
AB - A study was done on 30 patients with advanced adenocarcinoma of the prostate treated with diethylstilbestrol. Three groups of patients were given daily doses of 1, 5 and 1 times 3 mg. diethylstilbestrol, respectively. The study was confined to the effects of treatment on the levels of plasma testosterone by taking hormonal specimens every 4 hours for 24 hours. The results showed little difference of plasma testosterone among the groups under study and a statistical analysis showed no significant differences. Therefore, our study showed no appreciable advantage in the dosage spread over the day, compared to commonly used doses of 1 or 5 mg. diethylstilbestrol given in a single dosage.
UR - http://www.scopus.com/inward/record.url?scp=0018953066&partnerID=8YFLogxK
U2 - 10.1016/S0022-5347(17)56179-0
DO - 10.1016/S0022-5347(17)56179-0
M3 - Artículo
SN - 0022-5347
VL - 123
SP - 887
EP - 889
JO - Journal of Urology
JF - Journal of Urology
IS - 6
ER -