Double core infrared (CdSeTe) / ZnS quantum dots Conjugated to IgG antibodies

Double core CdSeTe/ZnS quantum dots (QDs) with emission at 800 nm have been studied by photoluminescence (PL) and Raman scattering methods in the non-conjugated state and after the conjugation to the IgG antibodies. The PL energy shift into the high energy range has been detected in PL spectra of bioconjugated QDs. Raman scattering spectra are studied with the aim to reveal the CdSeTe core compositions, as well as to design the QD energy diagrams. The QD energy diagrams permit to analysis PL spectra and their transformation at the bioconjugation of QDs. It is revealed that the interface in double core QDs has the type II quantum well character that permits to explain the IR optical transition (800nm) in CdSeTe QD core materials with relatively wide band gaps. It is shown that essential PL energy shift is promising for the study of QD bioconjugation with specific antibodies and can be a powerful technique in biology and early medical diagnostics.