TY - JOUR
T1 - Diuretic activity of aqueous extract and smoothie preparation of verbesina crocata in rat
AU - Salazar-Gómez, Anuar
AU - Pablo-Pérez, Saudy Saret
AU - Estévez-Carmona, María Mirian
AU - Meléndez-Camargo, María Estela
N1 - Publisher Copyright:
© 2018, Bangladesh Pharmacological Society. All rights reserved.
PY - 2018
Y1 - 2018
N2 - The aim of this study was to evaluate the diuretic activity of aqueous extract of Verbesina crocata at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular filtration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.
AB - The aim of this study was to evaluate the diuretic activity of aqueous extract of Verbesina crocata at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular filtration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.
UR - http://www.scopus.com/inward/record.url?scp=85052600194&partnerID=8YFLogxK
U2 - 10.3329/bjp.v13i3.27584
DO - 10.3329/bjp.v13i3.27584
M3 - Artículo
AN - SCOPUS:85052600194
SN - 1991-007X
VL - 13
SP - 236
EP - 240
JO - Bangladesh Journal of Pharmacology
JF - Bangladesh Journal of Pharmacology
IS - 3
ER -