Diuretic activity of aqueous extract and smoothie preparation of verbesina crocata in rat

Anuar Salazar-Gómez, Saudy Saret Pablo-Pérez, María Mirian Estévez-Carmona, María Estela Meléndez-Camargo

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The aim of this study was to evaluate the diuretic activity of aqueous extract of Verbesina crocata at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular filtration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.

Original languageEnglish
Pages (from-to)236-240
Number of pages5
JournalBangladesh Journal of Pharmacology
Volume13
Issue number3
DOIs
StatePublished - 2018

Fingerprint

Dive into the research topics of 'Diuretic activity of aqueous extract and smoothie preparation of verbesina crocata in rat'. Together they form a unique fingerprint.

Cite this