TY - JOUR
T1 - Diabetic nephropathy is ameliorated with peppermint (Mentha piperita) infusions prepared from salicylic acid-elicited plants
AU - Figueroa-Pérez, Marely G.
AU - Pérez-Ramírez, Iza F.
AU - Enciso-Moreno, José A.
AU - Gallegos-Corona, Marco A.
AU - Salgado, Luis M.
AU - Reynoso-Camacho, Rosalía
N1 - Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2018/4
Y1 - 2018/4
N2 - Different alternatives are used to delay diabetic complications, and the functional foods have an important position due to their beneficial effects. For instance, herbal infusions are used widely to improve the health, and their favorable effects are enhanced by plant elicitation during cultivation. Peppermint (Mentha pipperita) infusions prepared from elicited plants (2 mM salicylic acid) increased their content of several compounds, principally p-hydroxybenzoic and rosmarinic acids, hesperidin, quercetin-3-O-glucoside, α-tocopherol, and β-sitosterol. The administration of these infusions decreased microalbumin and urea in urine and serum uric acid levels, and the renal accumulation of 14 inflammation-related proteins. These proteins were associated with glomerular hypertrophy, tubular damage, expansion of mesangial matrix, and cell death. The application of 2 mM SA during peppermint cultivation improved the renoprotective properties of peppermint infusions.
AB - Different alternatives are used to delay diabetic complications, and the functional foods have an important position due to their beneficial effects. For instance, herbal infusions are used widely to improve the health, and their favorable effects are enhanced by plant elicitation during cultivation. Peppermint (Mentha pipperita) infusions prepared from elicited plants (2 mM salicylic acid) increased their content of several compounds, principally p-hydroxybenzoic and rosmarinic acids, hesperidin, quercetin-3-O-glucoside, α-tocopherol, and β-sitosterol. The administration of these infusions decreased microalbumin and urea in urine and serum uric acid levels, and the renal accumulation of 14 inflammation-related proteins. These proteins were associated with glomerular hypertrophy, tubular damage, expansion of mesangial matrix, and cell death. The application of 2 mM SA during peppermint cultivation improved the renoprotective properties of peppermint infusions.
KW - Diabetic nephropathy
KW - Elicitor
KW - Inflammation
KW - Oxidative stress
KW - Peppermint infusions
UR - http://www.scopus.com/inward/record.url?scp=85041603393&partnerID=8YFLogxK
U2 - 10.1016/j.jff.2018.01.029
DO - 10.1016/j.jff.2018.01.029
M3 - Artículo
AN - SCOPUS:85041603393
SN - 1756-4646
VL - 43
SP - 55
EP - 61
JO - Journal of Functional Foods
JF - Journal of Functional Foods
ER -