Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures

D. A. Fabila, J. M. De La Rosa, S. Stolik, E. Moreno, T. López, M. Álvarez, A. Arellano, G. De La Rosa, R. Mercado, J. L. Soto

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

In this paper we present the development of a portable spectrofluorometer with USB interface for in vivo measurements in biological tissue. The equipment consists of a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm with a resolution of 0.5 nm FWHM. As the excitation source a light emitting diode at 365 nm, with maximum radiant power of 200 mW was used. A bifurcated fiber optic (R200-UV/VIS) with six 200 μm diameter irradiation fibers and one 200 μm collection fiber is used. The system is powered and controlled with a laptop, avoiding the use of an external power supply. A program to select the light source, to process and measure spectra in real time was developed using the graphic language G of LabVIEW 8.2. Also, in this issue are presented in vivo measurements of diffuse reflection and fluorescence of non-neoplastic and neoplastic cerebral tissue of patients affected with glioblastoma multiform tumors (GBM). © 2010 IEEE.
Original languageAmerican English
DOIs
StatePublished - 1 Dec 2010
Event2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010 -
Duration: 1 Dec 2010 → …

Conference

Conference2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010
Period1/12/10 → …

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Ultraviolet spectrometers
Tissue
Fibers
Full width at half maximum
Fiber optics
Light emitting diodes
Light sources
Tumors
Fluorescence
Irradiation

Cite this

Fabila, D. A., De La Rosa, J. M., Stolik, S., Moreno, E., López, T., Álvarez, M., ... Soto, J. L. (2010). Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures. Paper presented at 2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010, . https://doi.org/10.1109/CASME.2010.5706669
Fabila, D. A. ; De La Rosa, J. M. ; Stolik, S. ; Moreno, E. ; López, T. ; Álvarez, M. ; Arellano, A. ; De La Rosa, G. ; Mercado, R. ; Soto, J. L. / Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures. Paper presented at 2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010, .
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Fabila, DA, De La Rosa, JM, Stolik, S, Moreno, E, López, T, Álvarez, M, Arellano, A, De La Rosa, G, Mercado, R & Soto, JL 2010, 'Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures', Paper presented at 2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010, 1/12/10. https://doi.org/10.1109/CASME.2010.5706669

Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures. / Fabila, D. A.; De La Rosa, J. M.; Stolik, S.; Moreno, E.; López, T.; Álvarez, M.; Arellano, A.; De La Rosa, G.; Mercado, R.; Soto, J. L.

2010. Paper presented at 2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010, .

Research output: Contribution to conferencePaper

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AU - Fabila, D. A.

AU - De La Rosa, J. M.

AU - Stolik, S.

AU - Moreno, E.

AU - López, T.

AU - Álvarez, M.

AU - Arellano, A.

AU - De La Rosa, G.

AU - Mercado, R.

AU - Soto, J. L.

PY - 2010/12/1

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N2 - In this paper we present the development of a portable spectrofluorometer with USB interface for in vivo measurements in biological tissue. The equipment consists of a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm with a resolution of 0.5 nm FWHM. As the excitation source a light emitting diode at 365 nm, with maximum radiant power of 200 mW was used. A bifurcated fiber optic (R200-UV/VIS) with six 200 μm diameter irradiation fibers and one 200 μm collection fiber is used. The system is powered and controlled with a laptop, avoiding the use of an external power supply. A program to select the light source, to process and measure spectra in real time was developed using the graphic language G of LabVIEW 8.2. Also, in this issue are presented in vivo measurements of diffuse reflection and fluorescence of non-neoplastic and neoplastic cerebral tissue of patients affected with glioblastoma multiform tumors (GBM). © 2010 IEEE.

AB - In this paper we present the development of a portable spectrofluorometer with USB interface for in vivo measurements in biological tissue. The equipment consists of a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm with a resolution of 0.5 nm FWHM. As the excitation source a light emitting diode at 365 nm, with maximum radiant power of 200 mW was used. A bifurcated fiber optic (R200-UV/VIS) with six 200 μm diameter irradiation fibers and one 200 μm collection fiber is used. The system is powered and controlled with a laptop, avoiding the use of an external power supply. A program to select the light source, to process and measure spectra in real time was developed using the graphic language G of LabVIEW 8.2. Also, in this issue are presented in vivo measurements of diffuse reflection and fluorescence of non-neoplastic and neoplastic cerebral tissue of patients affected with glioblastoma multiform tumors (GBM). © 2010 IEEE.

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Fabila DA, De La Rosa JM, Stolik S, Moreno E, López T, Álvarez M et al. Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures. 2010. Paper presented at 2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop, CASME 2010, . https://doi.org/10.1109/CASME.2010.5706669