Design and synthesis of two azete derivatives using some chemical strategies

Lauro Figueroa-Valverde, Francisco Díaz-Cedillo, Marcela Rosas-Nexticapa, Maria Virginia Mateu-Armad, Maria López-Ramos, Tomas Lopez-Gutierrez, Magdalena Alvarez‐ramirez, Catalina Cervantes-Ortega, Regina Cauich-Carrillo

Research output: Contribution to journalArticlepeer-review


There are several methods for preparing nitrogen-containing four-membered heterocycles using some reagents that require special conditions such as higher temperatures or differences in the pH. This research aimed to prepare two azete derivatives from 1-Bromo-3,5-dinitrobenzene using some chemical strategies. The chemical structure was characterized by NMR spectroscopic methods. The results indicate that protocols used to synthesize two azete analogs do not require special conditions to give a good yielding. In conclusion, is reported a facile method for the synthesis of two azete derivatives.

Original languageEnglish
Pages (from-to)5567-5578
Number of pages12
JournalBiointerface Research in Applied Chemistry
Issue number4
StatePublished - 15 Aug 2022


  • Azete
  • Four-membered
  • Heterocyclic
  • Synthesis


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