Design and synthesis of naphthol derivative

Lauro Figueroa-Valverde, F. Díaz-Cedillo, E. García-Cervera, E. Pool Gómez, Marcela Rosas-Nexticapan, M. Ramos-López

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11 Citations (Scopus)

Abstract

In this study a naphthalene derivative was synthetized using several strategies; in first stage a steroid derivative (3) was development by the reaction between androsterone and ethylenediamine using boric acid as catalyst. In the second stage compound 3 was used in the three-component system (β-naphthol, benzaldehyde and compound 3) for the synthesis of 17-(2-[[(2-hydroxy-naphtalen-1-yl)-phenyl-methyl] amino]ethylamino)-10,13- dimethyl-2,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a] -phenanthren-3-ol (6). In addition, a second method was used to form 6. In this technique 1-[(2-amino-ethylamino)-phenyl-methyl]-naphthalen-2-ol was made reacting with androsterone to form 6 using boric acid as catalyst. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. © 2013 Asian Journal of Chemistry.
Original languageAmerican English
Pages (from-to)6724-6726
Number of pages6051
JournalAsian Journal of Chemistry
StatePublished - 17 Jul 2013

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Androsterone
Naphthols
ethylenediamine
Derivatives
Catalysts
Steroids
boric acid
naphthalene
benzaldehyde

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Figueroa-Valverde, L., Díaz-Cedillo, F., García-Cervera, E., Gómez, E. P., Rosas-Nexticapan, M., & Ramos-López, M. (2013). Design and synthesis of naphthol derivative. Asian Journal of Chemistry, 6724-6726.
Figueroa-Valverde, Lauro ; Díaz-Cedillo, F. ; García-Cervera, E. ; Gómez, E. Pool ; Rosas-Nexticapan, Marcela ; Ramos-López, M. / Design and synthesis of naphthol derivative. In: Asian Journal of Chemistry. 2013 ; pp. 6724-6726.
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Figueroa-Valverde, L, Díaz-Cedillo, F, García-Cervera, E, Gómez, EP, Rosas-Nexticapan, M & Ramos-López, M 2013, 'Design and synthesis of naphthol derivative', Asian Journal of Chemistry, pp. 6724-6726.

Design and synthesis of naphthol derivative. / Figueroa-Valverde, Lauro; Díaz-Cedillo, F.; García-Cervera, E.; Gómez, E. Pool; Rosas-Nexticapan, Marcela; Ramos-López, M.

In: Asian Journal of Chemistry, 17.07.2013, p. 6724-6726.

Research output: Contribution to journalArticle

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Figueroa-Valverde L, Díaz-Cedillo F, García-Cervera E, Gómez EP, Rosas-Nexticapan M, Ramos-López M. Design and synthesis of naphthol derivative. Asian Journal of Chemistry. 2013 Jul 17;6724-6726.