Cross talk between proliferative, angiogenic, and cellular mechanisms orchestred by HIF-1 in Psoriasis

Azael Torales-Cardeña, Isaí Martínez-Torres, Sandra Rodríguez-Martínez, Fernando Gómez-Chávez, Juan C. Cancino-Díaz, Ernesto A. Vázquez-Sánchez, Mario E. Cancino-Díaz

Research output: Contribution to journalScientific review

12 Scopus citations

Abstract

© 2015 Azael Torales-Cardeña et al. Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor "hypoxia-inducible factor 1-Alpha" (HIF-1) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1 in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed.
Original languageAmerican English
JournalMediators of inflammation
DOIs
StatePublished - 1 Jan 2015

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