TY - JOUR
T1 - Cross talk between proliferative, angiogenic, and cellular mechanisms orchestred by HIF-1 in Psoriasis
AU - Torales-Cardeña, Azael
AU - Martínez-Torres, Isaí
AU - Rodríguez-Martínez, Sandra
AU - Gómez-Chávez, Fernando
AU - Cancino-Díaz, Juan C.
AU - Vázquez-Sánchez, Ernesto A.
AU - Cancino-Díaz, Mario E.
N1 - Publisher Copyright:
© 2015 Azael Torales-Cardeña et al.
PY - 2015
Y1 - 2015
N2 - Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor "hypoxia-inducible factor 1-Alpha" (HIF-1) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1 in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed.
AB - Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor "hypoxia-inducible factor 1-Alpha" (HIF-1) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1 in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed.
UR - http://www.scopus.com/inward/record.url?scp=84934899461&partnerID=8YFLogxK
U2 - 10.1155/2015/607363
DO - 10.1155/2015/607363
M3 - Artículo de revisión
C2 - 26136626
SN - 0962-9351
VL - 2015
JO - Mediators of Inflammation
JF - Mediators of Inflammation
M1 - 607363
ER -