Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide

Myrna Déciga-Campos; Gabriel Navarrete-Vázquez; Francisco Javier López-Muñoz; Tadeusz Librowski; Amanda Sánchez-Recillas; Victor Yañez-Pérez; Rolffy Ortiz-Andrade

doi:10.1016/j.dib.2016.07.019

Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide

Myrna Déciga-Campos, Gabriel Navarrete-Vázquez, Francisco Javier López-Muñoz, Tadeusz Librowski, Amanda Sánchez-Recillas, Victor Yañez-Pérez, Rolffy Ortiz-Andrade

Escuela Superior de Medicina (ESM)

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine.

Original language	English
Pages (from-to)	1007-1012
Number of pages	6
Journal	Data in Brief
Volume	8
DOIs	https://doi.org/10.1016/j.dib.2016.07.019
State	Published - Sep 2016

Keywords

Lidocaine
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide
Toxicity

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10.1016/j.dib.2016.07.019

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Déciga-Campos, M., Navarrete-Vázquez, G., López-Muñoz, F. J., Librowski, T., Sánchez-Recillas, A., Yañez-Pérez, V., & Ortiz-Andrade, R. (2016). Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide. Data in Brief, 8, 1007-1012. https://doi.org/10.1016/j.dib.2016.07.019

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title = "Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide",

abstract = "This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” D{\'e}ciga-Campos M., Navarrete-V{\'a}zquez G., L{\'o}pez-Mu{\~n}oz F.J., Librowski T., S{\'a}nchez-Recillas A., Ya{\~n}ez-P{\'e}rez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine.",

keywords = "Lidocaine, N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, Toxicity",

author = "Myrna D{\'e}ciga-Campos and Gabriel Navarrete-V{\'a}zquez and L{\'o}pez-Mu{\~n}oz, {Francisco Javier} and Tadeusz Librowski and Amanda S{\'a}nchez-Recillas and Victor Ya{\~n}ez-P{\'e}rez and Rolffy Ortiz-Andrade",

note = "Publisher Copyright: {\textcopyright} 2016 The Authors",

year = "2016",

month = sep,

doi = "10.1016/j.dib.2016.07.019",

language = "Ingl{\'e}s",

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Déciga-Campos, M, Navarrete-Vázquez, G, López-Muñoz, FJ, Librowski, T, Sánchez-Recillas, A, Yañez-Pérez, V & Ortiz-Andrade, R 2016, 'Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide', Data in Brief, vol. 8, pp. 1007-1012. https://doi.org/10.1016/j.dib.2016.07.019

Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide. / Déciga-Campos, Myrna; Navarrete-Vázquez, Gabriel; López-Muñoz, Francisco Javier et al.
In: Data in Brief, Vol. 8, 09.2016, p. 1007-1012.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide

AU - Déciga-Campos, Myrna

AU - Navarrete-Vázquez, Gabriel

AU - López-Muñoz, Francisco Javier

AU - Librowski, Tadeusz

AU - Sánchez-Recillas, Amanda

AU - Yañez-Pérez, Victor

AU - Ortiz-Andrade, Rolffy

PY - 2016/9

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N2 - This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine.

AB - This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine.

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KW - N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide

KW - Toxicity

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U2 - 10.1016/j.dib.2016.07.019

DO - 10.1016/j.dib.2016.07.019

M3 - Artículo

C2 - 27995169

SN - 2352-3409

VL - 8

SP - 1007

EP - 1012

JO - Data in Brief

JF - Data in Brief

ER -

Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide

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Keywords

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