Antibacterial activity of pipemidic acid ions-MgFeAl layered double hydroxide hybrid against E. Coli and S. typhi

Alejandra Santana-Cruz, Jorge Luis Flores-Moreno, Roberto Guerra-González, María De Jesús Martínez-Ortiz

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bacteria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.

Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalJournal of the Mexican Chemical Society
Volume60
Issue number2
StatePublished - 1 Apr 2016
Externally publishedYes

Keywords

  • Antibacterial activity
  • Hybrid material
  • Intercalation
  • Layered double hydroxide
  • Pipemidic acid

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