TY - JOUR
T1 - Alopecia Areata. Current situation and perspectives
AU - Juárez-Rendón, Karina J.
AU - Sánchez, Gildardo Rivera
AU - Reyes-López, Miguel
AU - García-Ortiz, José E.
AU - Bocanegra-García, Virgilio
AU - Guardiola-Avila, Iliana
AU - Altamirano-García, María L.
N1 - Publisher Copyright:
© 2017 Sociedad Argentina de Pediatria. All rights reserved.
PY - 2017/12
Y1 - 2017/12
N2 - Alopecia areata (AA) is a dermatological disease characterized by non-scarring hair loss of the scalp and/or body, with an unpredictable and variable evolution in the patients in which, despite multidisciplinary efforts, its etiology is not entirely known, although some evidence suggests that environmental, immunological and genetic factors could be generating the disease. The aim of this review is to provide an updated panorama of the clinical characteristics, diagnosis and treatment of AA, to analyze the mechanisms that could participate in its etiology, as well as to review some of the most important genetic variants that could confer susceptibility to the development of this disease.
AB - Alopecia areata (AA) is a dermatological disease characterized by non-scarring hair loss of the scalp and/or body, with an unpredictable and variable evolution in the patients in which, despite multidisciplinary efforts, its etiology is not entirely known, although some evidence suggests that environmental, immunological and genetic factors could be generating the disease. The aim of this review is to provide an updated panorama of the clinical characteristics, diagnosis and treatment of AA, to analyze the mechanisms that could participate in its etiology, as well as to review some of the most important genetic variants that could confer susceptibility to the development of this disease.
KW - Alopecia Areata
KW - Genes
KW - Susceptibility
UR - http://www.scopus.com/inward/record.url?scp=85049906298&partnerID=8YFLogxK
U2 - 10.5546/AAP.2017.ENG.E404
DO - 10.5546/AAP.2017.ENG.E404
M3 - Artículo de revisión
SN - 0325-0075
VL - 115
SP - E404-E411
JO - Archivos Argentinos de Pediatria
JF - Archivos Argentinos de Pediatria
IS - 6
ER -