Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst

María Adelina Jiménez-Arellanes, Lilián Yépez-Mulia, Julieta Luna-Herrera, Gabriel Alfonso Gutiérrez-Rebolledo, Rosa Virginia García-Rodríguez

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4 Citations (Scopus)

Abstract

Moussonia deppeana is known as tlachichinole, clachichinole, etc. In Mexican traditional medicine is used to treat gastrointestinal disorders, cough, stomach and duodenal ulcers, kidney and vaginal infections. The organic extracts prepared by maceration were evaluated against 11 mycobacterial strains and three protozoal. The AcOEt extract was active against Mycobacterium tuberculosis H37Rv, etambutol-resistant of H37Rv, and the clinical isolate SIN4 showed MIC=12.5 μg/mL, and against MMDO showed an MIC = 25 μg/mL. The Hex extract resulted moderately active against ethambutol-resistant of H37Rv and clinical isolates SIN4 and MMDO (MIC = 25 μg/mL). The Hex, AcOEt, and EtOH extracts were inactive against non-tuberculous mycobacterium strains showed MIC >50 μg/mL and against Giardia lamblia, Entamoeba histolytica, and Trichomona vaginalis showed IC50 >200 μg/mL. M. deppeana biosynthesized compounds with antimycobacterial activity.
Original languageAmerican English
Pages (from-to)31-35
Number of pages27
JournalRevista Mexicana de Ciencias Farmaceuticas
StatePublished - 1 Jan 2013

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cough
ulcers
tuberculosis
stomach
Giardia lamblia
Ethambutol
Entamoeba histolytica
kidneys
Traditional Medicine
infectious diseases
Stomach Ulcer
Mycobacterium
Duodenal Ulcer
medicine
Mycobacterium tuberculosis
Cough
Inhibitory Concentration 50
disorders
Kidney
Infection

Cite this

Jiménez-Arellanes, M. A., Yépez-Mulia, L., Luna-Herrera, J., Gutiérrez-Rebolledo, G. A., & García-Rodríguez, R. V. (2013). Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst. Revista Mexicana de Ciencias Farmaceuticas, 31-35.
Jiménez-Arellanes, María Adelina ; Yépez-Mulia, Lilián ; Luna-Herrera, Julieta ; Gutiérrez-Rebolledo, Gabriel Alfonso ; García-Rodríguez, Rosa Virginia. / Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst. In: Revista Mexicana de Ciencias Farmaceuticas. 2013 ; pp. 31-35.
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abstract = "Moussonia deppeana is known as tlachichinole, clachichinole, etc. In Mexican traditional medicine is used to treat gastrointestinal disorders, cough, stomach and duodenal ulcers, kidney and vaginal infections. The organic extracts prepared by maceration were evaluated against 11 mycobacterial strains and three protozoal. The AcOEt extract was active against Mycobacterium tuberculosis H37Rv, etambutol-resistant of H37Rv, and the clinical isolate SIN4 showed MIC=12.5 μg/mL, and against MMDO showed an MIC = 25 μg/mL. The Hex extract resulted moderately active against ethambutol-resistant of H37Rv and clinical isolates SIN4 and MMDO (MIC = 25 μg/mL). The Hex, AcOEt, and EtOH extracts were inactive against non-tuberculous mycobacterium strains showed MIC >50 μg/mL and against Giardia lamblia, Entamoeba histolytica, and Trichomona vaginalis showed IC50 >200 μg/mL. M. deppeana biosynthesized compounds with antimycobacterial activity.",
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Jiménez-Arellanes, MA, Yépez-Mulia, L, Luna-Herrera, J, Gutiérrez-Rebolledo, GA & García-Rodríguez, RV 2013, 'Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst', Revista Mexicana de Ciencias Farmaceuticas, pp. 31-35.

Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst. / Jiménez-Arellanes, María Adelina; Yépez-Mulia, Lilián; Luna-Herrera, Julieta; Gutiérrez-Rebolledo, Gabriel Alfonso; García-Rodríguez, Rosa Virginia.

In: Revista Mexicana de Ciencias Farmaceuticas, 01.01.2013, p. 31-35.

Research output: Contribution to journalArticleResearchpeer-review

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Jiménez-Arellanes MA, Yépez-Mulia L, Luna-Herrera J, Gutiérrez-Rebolledo GA, García-Rodríguez RV. Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst. Revista Mexicana de Ciencias Farmaceuticas. 2013 Jan 1;31-35.