A review of the impact of oxidative stress and some antioxidant therapies on renal damage

F. Tamay-Cach; J. C. Quintana-Pérez; J. G. Trujillo-Ferrara; R. I. Cuevas-Hernández; L. Del Valle-Mondragón; E. M. García-Trejo; M. G. Arellano-Mendoza

doi:10.3109/0886022X.2015.1120097

A review of the impact of oxidative stress and some antioxidant therapies on renal damage

F. Tamay-Cach, J. C. Quintana-Pérez, J. G. Trujillo-Ferrara, R. I. Cuevas-Hernández, L. Del Valle-Mondragón, E. M. García-Trejo, M. G. Arellano-Mendoza

Escuela Superior de Medicina (ESM)

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

An increase in the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) leads to complications during chronic kidney disease (CKD). This increase essentially derives from the impairment of natural antioxidant systems of the organism. The resulting oxidative stress produces damage to kidney tissue, especially by affecting nephrons and more generally by disrupting the function and structure of the glomerulus and interstitial tubule. This leads to a rapid decline in the condition of the patient and finally renal failure. Possible causes of kidney tissue damage are explored, as are different therapies, especially those related to the administration of antioxidants.

Original language	English
Pages (from-to)	171-175
Number of pages	5
Journal	Renal Failure
Volume	38
Issue number	2
DOIs	https://doi.org/10.3109/0886022X.2015.1120097
State	Published - 7 Feb 2016

Keywords

Oxidative stress
antioxidants
chronic kidney disease
glomerulus
renal damage

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title = "A review of the impact of oxidative stress and some antioxidant therapies on renal damage",

abstract = "An increase in the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) leads to complications during chronic kidney disease (CKD). This increase essentially derives from the impairment of natural antioxidant systems of the organism. The resulting oxidative stress produces damage to kidney tissue, especially by affecting nephrons and more generally by disrupting the function and structure of the glomerulus and interstitial tubule. This leads to a rapid decline in the condition of the patient and finally renal failure. Possible causes of kidney tissue damage are explored, as are different therapies, especially those related to the administration of antioxidants.",

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A review of the impact of oxidative stress and some antioxidant therapies on renal damage

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Keywords

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