TY - CONF
T1 - A pilot assay of interstitial photodynamic therapy with high-power laser system BioSpec® in a syngeneic breast cancer model
AU - Araujo-Padilla, Xelha
AU - Delgado-López, María Guadalupe
AU - Beltrán-Ortega, Carlos
AU - Ramón-Gallegos, Eva
PY - 2019/4/10
Y1 - 2019/4/10
N2 - © 2019 Author(s). Photodynamic therapy (PDT) is a new technique that has already been applied to several types of cancer, which combines a photosensitizer, light and oxygen. Interstitial PDT is based on intra-tumor light delivery using laser fibers inserted via needle. In this work, the fiber TF-N09 and the high-power laser system BIOSPEC® were tested in a syngeneic breast cancer mouse model. Results obtained in this work indicates that the irradiation causes necrosis in both groups, a group treated with pre-photosensitizer and a non-treated group. Also, the maximum potency usable with this device was 500mW, since at a higher power the needle reached temperatures above 37 °C.
AB - © 2019 Author(s). Photodynamic therapy (PDT) is a new technique that has already been applied to several types of cancer, which combines a photosensitizer, light and oxygen. Interstitial PDT is based on intra-tumor light delivery using laser fibers inserted via needle. In this work, the fiber TF-N09 and the high-power laser system BIOSPEC® were tested in a syngeneic breast cancer mouse model. Results obtained in this work indicates that the irradiation causes necrosis in both groups, a group treated with pre-photosensitizer and a non-treated group. Also, the maximum potency usable with this device was 500mW, since at a higher power the needle reached temperatures above 37 °C.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85064875935&origin=inward
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U2 - 10.1063/1.5095904
DO - 10.1063/1.5095904
M3 - Paper
T2 - AIP Conference Proceedings
Y2 - 24 July 2019
ER -
