A new germacranolide from Ageratina vernalis

Miguel Fuentes-Figueroa, Neively Tlapale-Lara, Beatriz Hernández-Carlos, Pedro Joseph-Nathan, Eleuterio Burgueño-Tapia

Research output: Contribution to journalArticlepeer-review


The aerial parts of Ageratina vernalis provided the new germacranolide 1,10-epoxydeltoidin A (3), together with the known pentacyclic triterpenoid hopane-6α,22-diol (1), and the also known germacranolides deltoidin A (2) and 15-hydroxydeltoidin A (4). In addition, pTsOH catalyzed cyclization of 2 afforded the new guaianolide 5. The absolute configuration of 2, 4, and 5 was assigned by vibrational circular dichroism spectroscopy, while the complete 1H and 13C NMR data assignments of 2-5 followed from 1 D- and 2 D-NMR experiments.

Original languageEnglish
JournalNatural Product Research
StateAccepted/In press - 2020


  • Ageratina vernalis
  • germacranolides
  • vibrational circular dichroism


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