A diffuse reflectance spectroscopy system to study biological tissues

A. De La Cadena, S. Stolik, J. M. De La Rosa

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Diffuse reflectance spectroscopy (DRS) is a technique that allows the study of the structural and biochemical condition of tissues in a noninvasive-nonionizing way. DRS has been widely used in biomedical applications, mainly as an alternative to biopsy. Generally, the technique consists in the irradiation of a specific zone of a tissue with a reference spectrum. Then, the reemitted by the tissue light is detected. The changes suffered by the backscattered spectrum (after light-tissue interaction) with respect to the incident one carry information about the tissue properties. This work presents a novel system designed and developed to use DRS in biomedical applications. The system uses a LED as a light source and a specially designed optical fiber probe as a mean to deliver the light to the tissue surface, and to collect the reemitted photons from the studied sample. This probe was designed to accomplish two different tasks: to increase the sensitivity of the diagnosis; and to study the radial dependence of the backscattered light. The measuring probe was built in a way that allows taking readings when the exerted pressure on the tissue reaches certain predetermined values.

Original languageEnglish
Title of host publication8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications
DOIs
StatePublished - 2013
Event8th Iberoamerican Optics Meeting, RIAO 2013 and 11th Latin American Meeting on Optics, Lasers, and Applications, OPTILAS 2013 - Porto, Portugal
Duration: 22 Jul 201326 Jul 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8785
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference8th Iberoamerican Optics Meeting, RIAO 2013 and 11th Latin American Meeting on Optics, Lasers, and Applications, OPTILAS 2013
Country/TerritoryPortugal
CityPorto
Period22/07/1326/07/13

Keywords

  • Biomedical Instruments
  • Diffuse Reflectance Spectroscopy
  • Optical Tissue Characterization

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