A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol

José C. Espinoza-Hicks, Gerardo Zaragoza-Galán, David Chávez-Flores, Víctor H. Ramos-Sánchez, Joaquín Tamariz, Alejandro A. Camacho-Dávila

Research output: Contribution to journalArticle

Abstract

© Georg Thieme Verlag Stuttgart · New York. All Rights Reserved. An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.
Original languageAmerican English
Pages (from-to)3493-3498
Number of pages3143
JournalSynthesis (Germany)
DOIs
StatePublished - 1 Jan 2018

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Benzofurans
Eugenol
Acylation
Biomass
ailanthoidol
homoegonol
benzofuran

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Espinoza-Hicks, J. C., Zaragoza-Galán, G., Chávez-Flores, D., Ramos-Sánchez, V. H., Tamariz, J., & Camacho-Dávila, A. A. (2018). A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol. Synthesis (Germany), 3493-3498. https://doi.org/10.1055/s-0037-1610169
Espinoza-Hicks, José C. ; Zaragoza-Galán, Gerardo ; Chávez-Flores, David ; Ramos-Sánchez, Víctor H. ; Tamariz, Joaquín ; Camacho-Dávila, Alejandro A. / A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol. In: Synthesis (Germany). 2018 ; pp. 3493-3498.
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A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol. / Espinoza-Hicks, José C.; Zaragoza-Galán, Gerardo; Chávez-Flores, David; Ramos-Sánchez, Víctor H.; Tamariz, Joaquín; Camacho-Dávila, Alejandro A.

In: Synthesis (Germany), 01.01.2018, p. 3493-3498.

Research output: Contribution to journalArticle

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