TY - JOUR
T1 - A convenient electrolytic process for the reduction of aldehydes
AU - Velázquez-Olvera, Stephania
AU - Salgado-Zamora, Hector
AU - Campos-Aldrete, María Elena
AU - Reyes-Arellano, Alicia
AU - Pérez-González, Cuauhtémoc
AU - Velázquez-Ponce, Manuel
N1 - Funding Information:
We thank the Consejo Nacional de Ciencia y Tecnología (Mexico) for financial support through project 49937. We are grateful to Dr Hernado Romero Paredes Rubio for all his comments. S.V-.O. thanks the Consejo Nacional de Ciencia y Tecnología for graduate scholarship No. 257526.
PY - 2014/7
Y1 - 2014/7
N2 - We report an efficient electrolytic procedure for the reduction of aldehydes to primary alcohols in the absence of dimeric products. In this promising approach, based on environmentally friendly chemical synthetic methods, a simple electrolytic undivided cell was designed. Two copper plates served as electrodes and recycled water as the medium. A 6-V battery provided the required energy. Although initially the method was intended for the preparation of 2-aryl-3-hydroxymethyl imidazo[1,2-a]azines, it was successfully extended to reduce other aliphatic and aromatic aldehydes. The attractiveness of this procedure includes its operational simplicity, practical viability, inexpensiveness and good yields. In most cases the results were better than those obtained with the standard reduction procedure using sodium borohydride.
AB - We report an efficient electrolytic procedure for the reduction of aldehydes to primary alcohols in the absence of dimeric products. In this promising approach, based on environmentally friendly chemical synthetic methods, a simple electrolytic undivided cell was designed. Two copper plates served as electrodes and recycled water as the medium. A 6-V battery provided the required energy. Although initially the method was intended for the preparation of 2-aryl-3-hydroxymethyl imidazo[1,2-a]azines, it was successfully extended to reduce other aliphatic and aromatic aldehydes. The attractiveness of this procedure includes its operational simplicity, practical viability, inexpensiveness and good yields. In most cases the results were better than those obtained with the standard reduction procedure using sodium borohydride.
KW - aliphatic aldehydes
KW - aryl and heteroaryl aldehydes
KW - copper anode and cathode
KW - electrolysis
KW - reduction
UR - http://www.scopus.com/inward/record.url?scp=84906337820&partnerID=8YFLogxK
U2 - 10.1080/17518253.2014.946973
DO - 10.1080/17518253.2014.946973
M3 - Carta
SN - 1751-8253
VL - 7
SP - 296
EP - 300
JO - Green Chemistry Letters and Reviews
JF - Green Chemistry Letters and Reviews
IS - 3
ER -