Abstract
A short and total synthesis of the natural carbazole mukonine (1) is described, based on a regioselective Diels-Alder reaction of N-phenyl 4,5-dimethylidene-2-oxazolidinone (9) with methyl propiolate (10). Successive transformation of the cycloadduct in one step to the corresponding phenylarylamine (16), and palladium promoted cyclization of the latter provided carbazole (1).
| Original language | English |
|---|---|
| Pages (from-to) | 259-267 |
| Number of pages | 9 |
| Journal | Heterocycles |
| Volume | 57 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1 Feb 2002 |